July 28th is World Hepatitis Day, created to raise understanding and awareness of what viral hepatitis is and what can be done about it.
Viral hepatitis is a term referring to any of several infections that attack your liver and cause damage to its’ cellular structure. The viruses we usually refer to when discussing viral hepatitis are: Hepatitis A, B, C, Delta and E. There are, however, other viruses that cause liver inflammation and, reversely, these five viruses can also cause damage and symptoms outside of the liver.
Viral hepatitis typically presents as an acute infection – there are some cases that are ‘subclinical’ meaning patients do not even have obvious symptoms and may go through an infection without ever knowing they had it! More commonly, however, patients present with symptoms including: fatigue, loss of appetite, nausea, vomiting, and jaundice (yellowing of the skin due to buildup of bilirubin – a pigment that your liver removes from the bloodstream when it is functioning properly). Very rarely, severe cases can even progress to liver failure, brain disease and may be fatal.
Many cases of acute hepatitis resolve within days, weeks or months. However, sometimes acute hepatitis can progress into chronic infection (this only happens with types B, C and Delta). Most often (85% of adult cases) this happens with Hepatitis C. In fact, infection with Hepatitis C can very often present only subclinically with patients experiencing only some fatigue and indigestion. Of course, the concern with these asymptomatic patients is that they may be spreading the infection without being aware of it.
The Delta virus is actually a co-infection that is only present along with Hepatitis B virus. Its presence is usually an indicator of more severe or chronic hepatitis B infection. It spreads through contact with infected blood (through injection or sexual contact)
Hepatitis A is spread primarily through infected food, water or close physical contact with another infected person. It is most common in areas with poor sanitation, such as developing countries or amongst injection drug users. This infection only presents as an acute illness and does not progress to chronic infection.
Hepatitis E is similar to A in that it does not progress to chronic infection and is typically spread through contaminated water, although you can also get this infection by eating contaminated animal products or transfusion of infected blood. This infection is most common in Asia. This infection is most dangerous for pregnant women – the virus can cross the placenta and infect the fetus. Due to immune system changes during pregnancy, pregnant women are more at risk to have severe consequences such as liver failure. Infection in the 3rd trimester can be fatal.
Hepatitis B is transmitted through infected blood or bodily fluid contact – this means both sexual and percutaneous transmission is possible. In some developing countries, dentists with inadequate sterilization equipment can be a source of infection. In general, since hepatitis B can live outside of the body for up to 7 days, any kind of intervention can potentially introduce the virus. This form of viral hepatitis can also develop into a chronic infection; an estimated 240 million people worldwide have chronic hepatitis B. Children under 6 years of age are most likely to develop chronic hepatitis B if they are infected.
Hepatitis C is a blood borne infection – you can only get it through unscreened blood transfusion, unsafe injection practices or unsterilized medical equipment. It can also travel through the placenta of an infected mother and cause infection in her baby. This form of hepatitis can be considered the most dangerous since it can often go undetected for decades as a chronic, asymptomatic infection.
Can hepatitis be cured?
We now have the medications available to clear most patients of their viral hepatitis. Most of the viral infections require only supportive therapy – making sure patients are hydrated and other symptoms – such as nausea and vomiting are reduced. Anti-viral therapies have been shown to be helpful for severe or chronic cases of Hepatitis B. We also now have treatment targeted at Hepatitis C that has made this infection curable as well.
Of course, with severe forms of hepatitis, patients have to be well enough to respond to available medications and fully recover. Some patients will also have irreversible damage from the infection, such as liver failure. Therefore, the best thing is to never become infected in the first place!
What can I do?
First and foremost you should know your status. Get tested for hepatitis B and C to ensure that you are not an asymptomatic carrier of this infection – knowing your status is the best way to protect your partners and future children.
If you are travelling out of the country, schedule a travel visit to find out if your travels will be through an area where Hepatitis A and E are common – this will alert you to be mindful of sanitation shortcomings, make sure you do not eat undercooked food or water that has not been sterilized.
If you are an injection drug user, please use safe practices by not sharing needles. You should also be mindful in any place that uses needles – if you are getting tattoos or piercing, make sure your provider uses proper sanitation techniques.
Healthcare workers are a special risk category for hepatitis infection since they are in contact with patients all the time. For this reason, make sure you are always using proper protection equipment (masks, gloves, eye shields) when working with patients.
Lastly, and most importantly – get vaccinated. Hepatitis A vaccines are available for patients travelling to endemic areas to make your trip worry-free. Hepatitis B vaccinations are available starting from birth! You can get your newborn vaccinated before they ever leave the hospital. Remember – Hepatitis B can live for up to 7 days outside of the body, so your baby can be at risk anytime they are in need of medical intervention – by vaccinating your baby, you can remove this risk-factor entirely. Healthcare workers who have not been vaccinated, should also get the vaccine series so that you can be safe and secure in your work. There is also a vaccine for Hepatitis E in China that will hopefully soon be available worldwide.
Viral hepatitis can be a mild inconvenience for some patients and a life-changing consequence for others, however, now that we have new treatments available, it is no longer a death sentence. Protect yourself by knowing your status and your options – schedule an appointment with one of our providers today!